%PDF-1.4
%
1 0 obj
<>>>
endobj
2 0 obj
<>stream
uuid:25363366-bad8-4890-81f2-04cd1a341ceb
adobe:docid:indd:2ab6f463-35e5-11df-81fa-914becda98c8
xmp.id:bf05aaa5-e44a-6b43-b870-c2aab8fee3fd
proof:pdf
xmp.iid:1b918d28-bb6e-6b4b-9d0d-e4f4db9ca523
xmp.did:7022DFC35D9BE411A111C5DCB0077B45
adobe:docid:indd:2ab6f463-35e5-11df-81fa-914becda98c8
default
converted
from application/x-indesign to application/pdf
Adobe InDesign CC 2015 (Windows)
/
2018-09-06T10:40:16-07:00
2018-09-06T10:40:16-07:00
2018-09-06T10:40:16-07:00
2018-09-06T10:40:16-07:00
Adobe InDesign CC 2015 (Windows)
application/pdf
Adobe PDF Library 15.0
False
endstream
endobj
3 0 obj
<>
endobj
5 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/TrimBox[0.0 0.0 612.0 792.0]/Type/Page>>
endobj
6 0 obj
<>stream
q
/GS0 gs
0 TL/Fm0 Do
Q
BT
/CS0 cs 0 0 0 1 scn
/GS1 gs
/T1_0 1 Tf
18 0 0 18 36 744.968 Tm
(AcroMetrix\231 EV)Tj
10.494 0 0 10.494 158.4709 750.962 Tm
( )Tj
18 0 0 18 160.8004 744.968 Tm
(Controls)Tj
7 0 0 7 36 723.212 Tm
[(For research use only)37.1 (. Not for use in diagnostic procedures. )]TJ
ET
q
0 0 612 792 re
W n
q 1 0 0 1 36 713.4121 cm
0 0 m
0.018 -9.506 l
16.507 -9.506 l
16.507 0 l
h
15.979 -0.519 m
15.979 -8.987 l
0.547 -8.987 l
0.545 -8.512 0.53 -0.995 0.53 -0.519 c
h
f
Q
q 1 0 0 1 38.63 711.3127 cm
0 0 m
2.133 0 l
3.214 0 3.585 -0.655 3.585 -1.383 c
3.585 -2.156 3.267 -2.535 2.677 -2.676 c
2.677 -2.691 l
3.487 -2.802 3.532 -3.3 3.548 -4.015 c
3.57 -5.063 3.608 -5.166 3.789 -5.241 c
3.789 -5.308 l
2.421 -5.308 l
2.322 -5.129 2.284 -4.832 2.284 -4.23 c
2.284 -3.308 2.156 -3.115 1.755 -3.115 c
1.271 -3.115 l
1.271 -5.308 l
0 -5.308 l
h
1.271 -2.238 m
1.664 -2.238 l
2.179 -2.238 2.315 -1.859 2.315 -1.546 c
2.315 -1.145 2.163 -0.877 1.657 -0.877 c
1.271 -0.877 l
h
f
Q
Q
q 1 0 0 1 42.9713 711.3127 cm
0 0 m
3.123 0 l
3.123 -1.011 l
1.271 -1.011 l
1.271 -2.074 l
3.011 -2.074 l
3.011 -3.085 l
1.271 -3.085 l
1.271 -4.296 l
3.207 -4.296 l
3.207 -5.308 l
0 -5.308 l
h
f
Q
q 1 0 0 1 46.7525 711.3127 cm
0 0 m
3.124 0 l
3.124 -1.011 l
1.271 -1.011 l
1.271 -2.074 l
3.011 -2.074 l
3.011 -3.085 l
1.271 -3.085 l
1.271 -5.308 l
0 -5.308 l
h
f
Q
BT
/T1_1 1 Tf
/Span<>> BDC
7 0 0 7 52.5068 705.9058 Tm
( )Tj
EMC
0.499 0.143 Td
(950499 AcroMetrix EV Negative Control)Tj
/Span<>> BDC
-2.857 -1.2 Td
( )Tj
EMC
2.857 0 Td
(950500 AcroMetrix EV Low Control)Tj
/T1_0 1 Tf
8 0 0 8 36 655.1058 Tm
(Product Use)Tj
/T1_1 1 Tf
0.008 Tc 0.011 Tw 7 0 0 7 36 646.7058 Tm
[(The AcroMetrix\231 EV Controls are intended for use in assessing the per\
formance of nucleic)8 ( )]TJ
0.009 Tc 0 -1.2 TD
[(a)0.5 (c)0.5 (id)0.5 ( t)0.5 (e)0.5 (st)0.5 ( p)0.5 (r)0.5 (o)0.5 (ce)0.5 (d)0.5 (u)0.5 (re)0.5 (s)0.5 ( f)0.5 (o)0.5 (r t)0.5 (h)0.5 (e)0.5 ( de)0.5 (t)0.5 (e)0.5 (rm)0.5 (i)0.5 (n)0.5 (a)0.5 (ti)0.6 (on)0.5 ( o)0.5 (f t)0.5 (h)0.5 (e)0.5 ( pr)0.5 (e)0.5 (s)0.5 (e)0.5 (nc)0.5 (e)0.5 ( o)0.5 (f e)0.5 (n)0.5 (t)0.5 (er)0.5 (o)0.5 (v)0.5 (i)0.5 (ru)0.5 (s)0.5 ( R)0.5 (N)0.5 (A.)0.5 ( R)0.5 (o)0.5 (u)0.5 (ti)0.5 (n)0.5 (e)0.5 ( u)0.5 (s)0.5 (e)8.9 ( )]TJ
0.013 Tc 0.013 Tw 0 -1.2 TD
[(of external run controls enables laboratories to monitor day-to-day test\
variation, lot-to-lot)13 ( )]TJ
0.017 Tc 0.018 Tw 0 -1.2 TD
[(performance )0.5 (of )0.5 (test )0.5 (kits, )0.5 (and operator variation, and )0.5 (can assist in )0.5 (identifying )0.5 (increases )0.5 (in)17 ( )]TJ
0 Tc 0 Tw 0 -1.2 TD
[(random or systematic error)70.2 (. For Research Use Only)37.1 (. Not for use in diagnostic procedures.)]TJ
/T1_0 1 Tf
8 0 0 8 36 595.7058 Tm
(Summary and Explanation)Tj
/T1_1 1 Tf
0.015 Tc 0.016 Tw 7 0 0 7 36 587.3058 Tm
[(The AcroMetrix EV Low Control contains inactivated human coxsackievirus \
particles from)15 ( )]TJ
0 Tc -0.014 Tw 0 -1.2 TD
[(strain CV)37 (A9. The AcroMetrix EV Low Control was produced by diluting quantitated e\
nterovirus )]TJ
0.034 Tc 0.033 Tw T*
[(s)0.5 (toc)0.5 (k i)0.5 (nto)0.5 ( Op)0.5 (tiM)0.5 (at)0.5 (ri)0.5 (x Cl)0.5 (ea)0.5 (r)70.4 (, a)0.5 ( pr)0.5 (opr)0.5 (ie)0.5 (tar)0.5 (y s)0.5 (yn)0.5 (the)0.5 (ti)0.5 (c ma)0.5 (tr)0.5 (ix)0.5 ( de)0.5 (sig)0.5 (ne)0.5 (d to)0.5 ( mi)0.5 (mi)0.5 (c na)0.5 (tu)0.5 (ral)0.5 (ly)34.1 ( )]TJ
0.02 Tc 0.021 Tw T*
[(occurring )0.5 (human )0.5 (cerebrospinal )0.5 (fluid )0.5 (\(CSF\) )0.5 (samples. )0.5 (The )0.5 (AcroMetrix )0.5 (EV )0.5 (Negative )0.5 (Control)20 ( )]TJ
0 Tc 0 Tw T*
[(contains only OptiMatrix Clear)70.2 (. )]TJ
0.024 Tc 0.024 Tw 0 -2.4 TD
[(Human )0.5 (Enterovirus )0.5 (is )0.5 (an )0.5 (RNA )0.5 (virus )0.5 (and )0.5 (a )0.5 (member )0.6 (of )0.5 (the )0.5 (Enterovirus )0.5 (genus )0.5 (of )0.5 (the )0.5 (family)24 ( )]TJ
0.021 Tc 0.02 Tw 0 -1.2 TD
[(Picornaviridae. This group includes the polioviruses, coxsackieviruses, \
echoviruses, and)21 ( )]TJ
0.02 Tc T*
[(other enteroviruses. The AcroMetrix EV Controls are designed as unassaye\
d controls for)20 ( )]TJ
0.021 Tc 0.021 Tw T*
[(use in qualitative molecular test procedures for enterovirus. The AcroMe\
trix EV Controls)21 ( )]TJ
0.017 Tc 0.017 Tw T*
[(help to ensure that nucleic acid testing results for enterovirus RNA are\
consistent across)17 ( )]TJ
0 Tc 0 Tw T*
(manufacturers, testing laboratories, operators, platforms and assay form\
ats.)Tj
/T1_0 1 Tf
8 0 0 8 36 477.5058 Tm
(Principles of the Procedure)Tj
/T1_1 1 Tf
0.031 Tc 0.031 Tw 7 0 0 7 36 469.1058 Tm
[(The AcroMetrix EV Controls have been formulated to mimic naturally occur\
ring human)31 ( )]TJ
0.018 Tc 0.019 Tw T*
[(samples containing enterovirus. Additionally)36.7 (, the intact virus format of the AcroMetrix EV)18 ( )]TJ
0.024 Tc 0.023 Tw T*
[(Lo)0.5 (w Co)0.5 (ntro)0.5 (l al)0.5 (low)0.5 (s fo)0.5 (r the)0.5 ( v)0.5 (er)0.5 (ifi)0.5 (cat)0.5 (ion)0.5 ( o)0.5 (f eff)0.5 (ect)0.5 (iv)0.5 (e vir)0.5 (al)0.5 ( R)0.5 (NA ex)0.5 (tr)0.5 (acti)0.5 (on a)0.5 (nd pur)0.5 (if)0.5 (ica)0.5 (tio)0.5 (n.)]TJ
0 Tc 0 Tw 37.286 0 Td
( )Tj
0.005 Tc 0.011 Tw -37.286 -1.2 Td
[(The controls are designed to monitor all procedural steps in test proced\
ures for determining)5 ( )]TJ
0 Tc -0.016 Tw T*
(the presence of enterovirus RNA in human specimens. Since the low positi\
ve control contains )Tj
0.006 Tw T*
(intact, encapsidated viral particles, the test methodology must include \
an extraction step that )Tj
0.015 Tc 0.016 Tw T*
[(releases the viral RNA for transcription, ampli\037cation and detection,\
as appropriate to the)15 ( )]TJ
0 Tc 0 Tw T*
(test.)Tj
0.002 Tc 0.012 Tw 0 -2.4 TD
[(The )0.5 (AcroMetrix )0.5 (EV Low Positive )0.5 (Control )0.5 (contains )0.5 (inactivated )0.6 (enterovirus. )0.5 (The )0.5 (control has )0.5 (no)2 ( )]TJ
0.012 Tc 0 -1.2 TD
[(assigned value since currently no generally accepted international enter\
ovirus standard is)12 ( )]TJ
0.004 Tc 0.011 Tw T*
[(available. Consistency is achieved by calibrating each lot against a hig\
hly stable enterovirus)4 ( )]TJ
0 Tc 0 Tw T*
(standard assigned at 100 EVU/mL \(Enterovirus Units per mL\).)Tj
0.002 Tc 0.011 Tw 0 -2.4 TD
[(E)0.5 (x)0.5 (p)0.5 (ec)0.5 (t)0.5 (e)0.5 (d r)0.5 (e)0.5 (s)0.5 (u)0.5 (l)0.5 (ts)0.5 ( u)0.5 (t)0.5 (i)0.5 (l)0.5 (i)0.5 (z)0.5 (i)0.5 (ng)0.5 ( t)0.5 (he)0.5 ( A)0.5 (c)0.5 (r)0.5 (o)0.5 (Me)0.5 (t)0.5 (r)0.5 (i)0.5 (x)0.5 ( EV)0.5 ( C)0.5 (o)0.5 (n)0.5 (tr)0.5 (o)0.5 (l)0.5 (s)0.5 ( m)0.5 (u)0.5 (st)0.5 ( b)0.5 (e)0.5 ( e)0.5 (st)0.5 (a)0.5 (b)0.5 (l)0.5 (i)0.5 (s)0.5 (he)0.5 (d)0.5 ( b)0.5 (y)0.5 ( t)0.5 (h)0.5 (e)0.5 ( e)0.5 (nd)0.5 ( u)0.5 (s)0.5 (e)0.5 (r)0.5 ( f)0.5 (o)0.5 (r)2 ( )]TJ
0.006 Tc 0 -1.2 TD
[(their particular enterovirus RNA assay)37.2 (. The controls are for Research Use Only and DO NOT)6 ( )]TJ
0 Tc 0 Tw T*
[(HA)37 (VE ASSIGNED V)37 (ALUES.)]TJ
/T1_0 1 Tf
8 0 0 8 36 316.7058 Tm
(Reagents)Tj
ET
0 0 0 0.15 scn
/GS0 gs
36.25 312.456 55.19 -13.068 re
91.44 312.456 99.72 -13.068 re
191.16 312.456 65.88 -13.068 re
257.04 312.456 39.71 -13.068 re
f
/CS0 CS 0 0 0 1 SCN
0.5 w
/GS2 gs
q 1 0 0 1 36 312.4558 cm
0 0 m
55.44 0 l
S
Q
q 1 0 0 1 36.25 299.6378 cm
0 0 m
0 12.568 l
S
Q
q 1 0 0 1 91.44 312.4558 cm
0 0 m
99.72 0 l
S
Q
q 1 0 0 1 91.44 299.6378 cm
0 0 m
0 12.568 l
S
Q
q 1 0 0 1 191.16 312.4558 cm
0 0 m
65.88 0 l
S
Q
q 1 0 0 1 191.16 299.6378 cm
0 0 m
0 12.568 l
S
Q
q 1 0 0 1 257.04 312.4558 cm
0 0 m
39.96 0 l
S
Q
q 1 0 0 1 257.04 299.6378 cm
0 0 m
0 12.568 l
S
Q
q 1 0 0 1 296.75 299.6378 cm
0 0 m
0 12.568 l
S
Q
q 1 0 0 1 36 299.3878 cm
0 0 m
55.44 0 l
S
Q
q 1 0 0 1 36.25 286.5698 cm
0 0 m
0 12.568 l
S
Q
q 1 0 0 1 91.44 299.3878 cm
0 0 m
99.72 0 l
S
Q
q 1 0 0 1 91.44 286.5698 cm
0 0 m
0 12.568 l
S
Q
q 1 0 0 1 191.16 299.3878 cm
0 0 m
65.88 0 l
S
Q
q 1 0 0 1 191.16 286.5698 cm
0 0 m
0 12.568 l
S
Q
q 1 0 0 1 257.04 299.3878 cm
0 0 m
39.96 0 l
S
Q
q 1 0 0 1 257.04 286.5698 cm
0 0 m
0 12.568 l
S
Q
q 1 0 0 1 296.75 286.5698 cm
0 0 m
0 12.568 l
S
Q
q 1 0 0 1 36 286.3198 cm
0 0 m
55.44 0 l
S
Q
q 1 0 0 1 36.25 273.5018 cm
0 0 m
0 12.568 l
S
Q
q 1 0 0 1 91.44 286.3198 cm
0 0 m
99.72 0 l
S
Q
q 1 0 0 1 91.44 273.5018 cm
0 0 m
0 12.568 l
S
Q
q 1 0 0 1 191.16 286.3198 cm
0 0 m
65.88 0 l
S
Q
q 1 0 0 1 191.16 273.5018 cm
0 0 m
0 12.568 l
S
Q
q 1 0 0 1 257.04 286.3198 cm
0 0 m
39.96 0 l
S
Q
q 1 0 0 1 257.04 273.5018 cm
0 0 m
0 12.568 l
S
Q
q 1 0 0 1 296.75 273.5018 cm
0 0 m
0 12.568 l
S
Q
q 1 0 0 1 36 273.2518 cm
0 0 m
55.44 0 l
S
Q
q 1 0 0 1 91.44 273.2518 cm
0 0 m
99.72 0 l
S
Q
q 1 0 0 1 191.16 273.2518 cm
0 0 m
65.88 0 l
S
Q
q 1 0 0 1 257.04 273.2518 cm
0 0 m
39.96 0 l
S
Q
BT
0 0 0 1 scn
/GS1 gs
7 0 0 7 40.8991 303.3878 Tm
(Catalog Number)Tj
9.233 0 Td
(Enterovirus Control name)Tj
12.911 0 Td
(Control Designation)Tj
9.876 0 Td
(Quantity)Tj
/T1_1 1 Tf
-30.073 -1.867 Td
(950499)Tj
6.009 0 Td
(AcroMetrix EV Negative Control)Tj
/T1_0 1 Tf
18.05 0 Td
(-)Tj
/T1_1 1 Tf
5.794 0 Td
(5 x 0.3 mL)Tj
-29.853 -1.867 Td
(950500)Tj
6.982 0 Td
(AcroMetrix EV Low Control)Tj
/T1_0 1 Tf
16.994 0 Td
(+)Tj
/T1_1 1 Tf
5.877 0 Td
(5 x 0.3 mL)Tj
-32.499 -2.607 Td
(These products contain 0.5% ProClin\231 300 as a preservative.)Tj
ET
q
0 0 612 792 re
W n
q 1 0 0 1 41.7973 239.0208 cm
0 0 m
0.377 0 0.682 0.306 0.682 0.682 c
0.682 1.059 0.377 1.365 0 1.365 c
-0.377 1.365 -0.682 1.059 -0.682 0.682 c
-0.682 0.306 -0.377 0 0 0 c
f
Q
q 1 0 0 1 47.4867 238.84 cm
0 0 m
-4.952 8.54 l
-5.026 8.665 -5.128 8.767 -5.259 8.845 c
-5.679 9.086 -6.216 8.942 -6.457 8.523 c
-11.38 0 l
-11.445 -0.121 -11.487 -0.266 -11.487 -0.421 c
-11.487 -0.904 -11.092 -1.294 -10.609 -1.294 c
-0.767 -1.294 l
-0.287 -1.294 0.108 -0.904 0.108 -0.421 c
0.108 -0.266 0.068 -0.121 0 0 c
-10.639 -0.421 m
-5.706 8.202 l
-0.767 -0.421 l
h
f
Q
q 1 0 0 1 42.5843 244.1716 cm
0 0 m
0.032 -0.501 -0.064 -0.828 -0.118 -1.155 c
-0.533 -3.4 l
-1.023 -3.4 l
-1.458 -1.155 l
-1.537 -0.775 -1.559 -0.491 -1.603 -0.022 c
-1.625 0.38 -1.338 0.808 -0.803 0.808 c
-0.218 0.808 -0.033 0.393 0 0 c
f
Q
Q
BT
/T1_0 1 Tf
8 0 0 8 47.5946 237.5455 Tm
( )Tj
[(Precautions and W)18.1 (arning)]TJ
0.028 Tc -0.028 Tw 7 0 0 7 36 229.1455 Tm
(DANGER:)Tj
/T1_1 1 Tf
0.029 Tw [( )0.5 (Although )0.6 (the )0.6 (AcroMetrix )0.5 (EV )0.6 (Low )0.5 (Control )0.5 (contains )0.6 (inactivated )0.5 (enterovirus, )0.6 (all)28.1 ( )]TJ
0.001 Tc 0.011 Tw T*
[(AcroMetrix EV controls should be considered potentially biohazardous. Co\
ntains \0363% Human)1 ( )234 ( )]TJ
0.029 Tc 0.029 Tw T*
[(Serum )0.5 (Albumin )0.5 (\(HSA\), )0.6 (and )0.5 (\0360.05% )0.5 (ProClin\231 )0.5 (300. )0.5 (Observe )0.5 (the )0.6 (universal )0.5 (precautions )0.5 (for)29 ( )]TJ
0 Tc 0 Tw T*
(prevention of transmission of infectious agents when handling these mate\
rials.)Tj
4.081 0 0 4.081 256.0557 206.2766 Tm
(1, 2, 3)Tj
7 0 0 7 36 187.1455 Tm
(H317 - May cause allergic skin reaction.)Tj
0 -1.2 TD
(H334 - May cause allergy or asthma symptoms or breathing dif\037culties \
if inhaled.)Tj
0 -1.2 TD
(H412 - Harmful to aquatic life with long lasting effects.)Tj
0.009 Tc 0.011 Tw 0 -2.4 TD
[(A)25.1 (void breathing mist or vapor)70.1 (. Contaminated work clothing should not be allowed out of the)9 ( )]TJ
0.017 Tc 0.016 Tw 0 -1.2 TD
[(w)0.5 (or)0.5 (k)0.5 (pl)0.5 (a)0.5 (ce)0.5 (.)0.5 ( A)25.5 (vo)0.5 (i)0.5 (d re)0.5 (l)0.5 (ea)0.5 (s)0.5 (e to)0.5 ( t)0.5 (h)0.5 (e en)0.5 (vi)0.5 (r)0.5 (o)0.5 (nm)0.5 (en)0.5 (t)0.5 (. W)30.4 (e)0.5 (a)0.5 (r pr)0.5 (ot)0.5 (e)0.5 (ct)0.5 (i)0.5 (ve)0.5 ( gl)0.5 (ov)0.5 (e)0.5 (s/)0.5 (e)0.5 (ye)0.5 ( p)0.5 (r)0.5 (ot)0.5 (e)0.5 (ct)0.5 (io)0.5 (n)0.5 (/f)0.5 (ac)0.5 (e)17 ( )]TJ
0.016 Tc 0.017 Tw 0 -1.2 TD
[(protection. )0.5 (In )0.5 (case )0.5 (of )0.5 (inadequate )0.5 (ventilation )0.5 (wear )0.5 (respiratory )0.6 (protection. )0.5 (If )0.5 (on )0.6 (skin: )0.5 (W)29.8 (ash)16.1 ( )]TJ
0.005 Tc 0.011 Tw 0 -1.2 TD
[(with plenty of soap and water)70 (. IF INHALED: If breathing is dif\037cult, remove victim to fresh air)5 ( )]TJ
0.009 Tc 0 -1.2 TD
[(and keep at rest in a position comfortable for breathing. If skin irrita\
tion or rash occurs: Get)9 ( )]TJ
0.014 Tc 0.014 Tw 0 -1.2 TD
[(medical advice/attention: If experiencing respiratory symptoms: Call a P\
OISON CENTER or)14 ( )]TJ
0 Tc -0.02 Tw 0 -1.2 TD
[(doctor/physician. W)30 (ash contaminated clothing before reuse. Dispose of contents/container to\
)]TJ
0 Tw 0 -1.2 TD
(location in accordance with local/regional/national/international regula\
tions.)Tj
0.005 Tc 0.011 Tw 0 -2.4 TD
[(Do not pipette by mouth. Use personal protective equipment, including la\
b coats, gloves and)5 ( )]TJ
0 Tc 0 Tw 0 -1.2 TD
(safety glasses. Do not eat, drink or smoke in areas where panels and sam\
ples are handled.)Tj
0.01 Tc 0.011 Tw 0 -2.4 TD
[(Disinfect liquids, materials or spills with a 0.5% sodium hypochlorite s\
olution. Dispose of all)10 ( )]TJ
0 Tc 0 Tw 0 -1.2 TD
(materials and liquids used in the procedure as if they contained pathoge\
nic agents.)Tj
ET
0.35 w
q 1 0 0 1 442.3204 621.3081 cm
0 0 m
28.462 0 l
S
Q
BT
/T1_0 1 Tf
8 0 0 8 315 655.608 Tm
(Storage Instructions)Tj
/T1_1 1 Tf
0.02 Tc 0.02 Tw 7 0 0 7 315 647.208 Tm
[(It is recommended that the AcroMetrix EV Controls be stored at -70\260C \
or lower to ensure)20 ( )]TJ
0 Tc 0 Tw 0 -1.2 TD
(consistent results until the expiration date. )Tj
0.011 Tw 0 -2.4 TD
(The AcroMetrix EV Controls are designed for )Tj
/T1_2 1 Tf
(single use)Tj
/T1_1 1 Tf
( and excess material in each vial is to )Tj
0 Tw 0 -1.2 TD
(be appropriately discarded. )Tj
0 -2.4 TD
(Do not use these products beyond the expiration date printed on the tube\
label.)Tj
/T1_0 1 Tf
8 0 0 8 315 587.808 Tm
(Instructions for Use)Tj
/T1_1 1 Tf
0.037 Tw 7 0 0 7 315 579.408 Tm
[(Thaw the AcroMetrix EV Controls at room temperature, vortex brie\035y)37 (, and immediately place )]TJ
0 Tw 0 -1.2 TD
(on ice. )Tj
0.029 Tc 0.028 Tw 0 -2.4 TD
[(T)0.5 (h)0.5 (e)0.5 ( A)0.5 (c)0.5 (r)0.6 (o)0.5 (M)0.5 (e)0.5 (t)0.5 (r)0.5 (i)0.6 (x)0.5 ( E)0.5 (V)0.6 ( C)0.5 (o)0.5 (n)0.6 (t)0.5 (r)0.5 (o)0.5 (l)0.5 (s)0.6 ( s)0.5 (h)0.6 (o)0.5 (u)0.5 (l)0.5 (d)0.5 ( b)0.5 (e)0.5 ( h)0.5 (a)0.6 (n)0.5 (d)0.5 (l)0.5 (e)0.6 (d)0.5 ( a)0.5 (n)0.5 (d)0.6 ( t)0.5 (e)0.5 (s)0.6 (t)0.5 (e)0.5 (d)0.5 ( i)0.6 (n)0.5 ( a)0.5 ( m)0.5 (a)0.5 (n)0.5 (n)0.5 (e)0.6 (r)0.5 ( i)0.6 (d)0.5 (e)0.5 (n)0.5 (t)0.5 (i)0.5 (c)0.6 (a)0.5 (l)0.5 ( t)0.5 (o)0.5 ( t)0.5 (h)0.6 (a)0.5 (t)29 ( )]TJ
0.009 Tc 0.011 Tw 0 -1.2 TD
[(r)0.5 (equ)0.5 (ir)0.5 (ed)0.5 ( f)0.5 (or s)0.5 (am)0.5 (pl)0.5 (es)0.5 ( r)0.5 (un)0.5 ( i)0.5 (n the)0.5 ( ent)0.5 (er)0.5 (ov)0.5 (ir)0.5 (us R)0.5 (NA)0.5 ( te)0.5 (s)0.5 (t pro)0.5 (ce)0.5 (du)0.5 (re be)0.5 (in)0.5 (g ev)0.5 (al)0.5 (ua)0.5 (ted)0.5 (. F)0.5 (oll)0.5 (o)0.5 (w th)0.5 (e)8.9 ( )]TJ
0 Tc 0 Tw T*
[(manufacturer\222)74 (s instructions and recommendations for the handling and testing of sampl\
es.)]TJ
/T1_0 1 Tf
8 0 0 8 315 520.0081 Tm
(Limitations)Tj
/T1_1 1 Tf
0.044 Tc 0.043 Tw 7 0 0 7 315 511.608 Tm
[(Th)0.5 (e A)0.5 (cro)0.5 (Metr)0.5 (ix)0.5 ( E)0.5 (V C)0.5 (ont)0.5 (rol)0.5 (s are i)0.5 (nten)0.5 (ded fo)0.5 (r Res)0.5 (earc)0.5 (h U)0.5 (se)0.5 ( O)0.5 (nly)37.4 (,)0.5 ( a)0.5 (nd DO)0.5 ( N)0.5 (OT HA)37.4 (V)0.5 (E)44 ( )]TJ
0 Tc 0 Tw T*
[(ASSIGNED V)37 (ALUES. Not for use in diagnostic procedures)]TJ
/T1_0 1 Tf
8 0 0 8 315 485.808 Tm
(References)Tj
/T1_1 1 Tf
7 0 0 7 324 477.408 Tm
(1.)Tj
/Span<>> BDC
( )Tj
EMC
-0.005 Tc -0.056 Tw /Span<>> BDC
0.771 0 Td
( )Tj
EMC
1.029 0 Td
[(C)0.5 (e)0.5 (n)0.5 (t)0.5 (e)0.5 (rs)0.6 ( f)0.5 (or)0.5 ( D)0.5 (i)0.5 (s)0.5 (e)0.5 (a)0.5 (s)0.5 (e)0.5 ( C)0.5 (o)0.5 (n)0.5 (t)0.5 (r)0.5 (o)0.5 (l)0.5 ( \()0.5 (CD)0.5 (C)0.5 (\))0.5 (.)0.5 ( R)0.5 (e)0.5 (c)0.5 (o)0.5 (m)0.5 (m)0.5 (e)0.5 (n)0.5 (d)0.5 (at)0.6 (i)0.5 (on)0.5 (s)0.5 ( f)0.5 (o)0.5 (r)0.5 ( p)0.5 (r)0.5 (e)0.5 (v)0.5 (e)0.5 (n)0.5 (t)0.5 (i)0.5 (o)0.5 (n of)0.5 ( H)0.5 (I)0.5 (V)0.5 ( t)0.5 (r)0.5 (a)0.5 (n)0.5 (s)0.5 (m)0.5 (i)0.5 (s)0.5 (s)0.5 (i)0.5 (o)0.5 (n)-5 ( )]TJ
0 Tc 0 Tw T*
(in health care settings. MMWR 1987; 36 \(supplement no. 2S\).)Tj
-1.8 -1.2 Td
(2.)Tj
/Span<>> BDC
( )Tj
EMC
0.003 Tc 0.111 Tw /Span<>> BDC
0.771 0 Td
( )Tj
EMC
1.029 0 Td
[(C)0.5 (ent)0.5 (er)0.5 (s )0.5 (fo)0.5 (r )0.5 (Di)0.5 (se)0.5 (as)0.5 (e )0.5 (Co)0.5 (nt)0.5 (ro)0.5 (l )0.5 (\(C)0.5 (DC)0.5 (\).)0.5 ( U)0.5 (pd)0.5 (at)0.5 (e:)0.5 ( U)0.5 (ni)0.5 (v)0.5 (ers)0.5 (al)0.5 ( )0.5 (pr)0.5 (eca)0.5 (ut)0.5 (io)0.5 (ns)0.5 ( f)0.5 (or)0.5 ( p)0.5 (re)0.5 (ve)0.5 (nt)0.5 (io)0.5 (n )0.5 (of)3 ( )]TJ
0 Tc -0.051 Tw T*
(transmission of human immunode\037ciency virus, hepatitis B virus, and o\
ther bloodborne )Tj
0 Tw T*
(pathogens in health-care settings. MMWR 1988; 37:377-388.)Tj
-1.8 -1.2 Td
(3.)Tj
/Span<>> BDC
( )Tj
EMC
-0.006 Tw /Span<>> BDC
0.771 0 Td
( )Tj
EMC
1.029 0 Td
[(Centers for )0.5 (Disease )0.5 (Control \(CDC\). )0.5 (Guidelines for )0.5 (prevention )0.5 (of transmission )0.5 (of human )]TJ
-0.045 Tw T*
[(immunode\037ciency )0.6 (virus )0.6 (and )0.6 (hepatitis )0.6 (B )0.6 (virus )0.6 (to )0.6 (health-care )0.6 (and )0.5 (public-safety )0.6 (workers. )177.1 ( )]TJ
0 Tw T*
(MMWR 1989; 38\(S-6\): 1-36.)Tj
/T1_0 1 Tf
8 0 0 8 315 400.608 Tm
(Glossary:)Tj
/T1_1 1 Tf
7 0 0 7 315 392.208 Tm
[(http://www)37 (.thermo\037sher)70.1 (.com/symbols-glossary)]TJ
0.029 Tc 0.028 Tw 6 0 0 6 314.5 91.8606 Tm
[(\251 2018 Thermo Fisher Scientific Inc. All rights reserved. Proclin is \
a trademark of the Rohm and Haas)29 ( )]TJ
0 Tc 0 Tw T*
[(company)37 (. All other trademarks are the property of Thermo Fisher Scienti\037c or\
its af\037liates.)]TJ
7 0 0 7 342.6674 124.3992 Tm
(For insert updates go to:)Tj
T*
[(www)37 (.thermo\037sher)70.1 (.com/Acrometrix)]TJ
/Span<>> BDC
-3.929 12.211 Td
( )Tj
EMC
ET
q 1 0 0 1 318.5602 206.9343 cm
0 0 m
1.65 2.853 l
3.211 0 l
4.817 2.853 l
6.422 0 l
6.422 5.466 l
8.357 5.466 l
8.357 -5.459 l
-3.101 -5.447 l
-3.101 -0.075 l
-1.462 2.929 l
h
f
Q
BT
7 0 0 7 315.1674 193.075 Tm
(Microgenics Corporation)Tj
T*
(46500 Kato Road)Tj
T*
(Fremont, CA 94538 USA)Tj
T*
(US Customer and )Tj
T*
[(T)80 (echnical Support:)]TJ
T*
(1-800-232-3342)Tj
6.86 0 0 7 534.1002 44.2565 Tm
(MAN0004329-C)Tj
7 0 0 7 554.2449 35.8565 Tm
(2018 09)Tj
ET
endstream
endobj
14 0 obj
<>/ExtGState<>>>/Subtype/Form>>stream
/CS0 CS 0 0 0 1 SCN
0.5 w 4 M 0 j 0 J
/GS0 gs
q 1 0 0 1 404.28 84.384 cm
0 0 m
S
Q
/CS0 cs 0 0 0 1 scn
q 1 0 0 1 327.1247 128.5742 cm
0 0 m
-0.134 -0.112 -0.152 -0.312 -0.04 -0.446 c
0.071 -0.58 0.271 -0.597 0.405 -0.486 c
1.563 0.478 3.988 1.913 5.917 1.913 c
7.13 1.913 8.112 1.286 9.062 0.679 c
10.015 0.071 11.002 -0.559 12.215 -0.559 c
12.39 -0.559 12.531 -0.418 12.531 -0.243 c
12.531 -0.068 12.39 0.073 12.215 0.073 c
11.187 0.073 10.321 0.626 9.402 1.212 c
8.376 1.867 7.315 2.545 5.917 2.545 c
3.656 2.545 1.059 0.881 0 0 c
f
Q
q 1 0 0 1 318.1357 129.7874 cm
0 0 m
-0.919 -0.587 -1.786 -1.14 -2.817 -1.14 c
-3.133 -1.14 l
-3.133 -1.772 l
-2.817 -1.772 l
-1.603 -1.772 -0.615 -1.143 0.34 -0.534 c
1.334 0.101 2.273 0.7 3.486 0.7 c
5.411 0.7 7.832 -0.735 8.989 -1.699 c
9.232 -1.902 l
9.637 -1.416 l
9.394 -1.213 l
8.337 -0.333 5.742 1.332 3.486 1.332 c
2.088 1.332 1.026 0.654 0 0 c
f
Q
q 1 0 0 1 318.1349 118.9008 cm
0 0 m
-0.914 -0.585 -1.778 -1.137 -2.806 -1.137 c
-3.121 -1.137 l
-3.121 -1.769 l
-2.806 -1.769 l
-1.594 -1.769 -0.61 -1.14 0.341 -0.533 c
1.289 0.074 2.268 0.701 3.484 0.701 c
5.414 0.701 7.835 -0.734 8.991 -1.698 c
9.234 -1.901 l
9.639 -1.415 l
9.396 -1.212 l
8.34 -0.332 5.745 1.333 3.484 1.333 c
2.084 1.333 1.024 0.655 0 0 c
f
Q
315 117.128 0.632 11.519 re
f
q 1 0 0 1 339.0242 128.647 cm
0 0 m
0 -10.809 l
-0.887 -10.707 -1.681 -10.268 -2.497 -9.746 c
-3.525 -9.091 -4.587 -8.414 -5.986 -8.414 c
-8.243 -8.414 -10.841 -10.077 -11.899 -10.958 c
-12.142 -11.161 l
-11.737 -11.647 l
-11.494 -11.444 l
-10.336 -10.481 -7.912 -9.045 -5.986 -9.045 c
-4.772 -9.045 -3.788 -9.672 -2.838 -10.279 c
-1.884 -10.888 -0.898 -11.517 0.316 -11.517 c
0.49 -11.517 0.632 -11.376 0.632 -11.201 c
0.632 0 l
h
f
Q
q 1 0 0 1 333.7849 121.7291 cm
0 0 m
0 4.581 l
0.005 4.581 l
0.005 5.15 l
-2.471 5.15 l
-2.471 4.581 l
-1.668 4.581 l
-1.668 0 l
-2.425 0 l
-2.425 -0.575 l
0.929 -0.575 l
0.929 0 l
h
-0.765 5.661 m
-0.278 5.661 0.117 6.058 0.117 6.544 c
0.117 7.036 -0.278 7.431 -0.765 7.431 c
-1.254 7.431 -1.648 7.036 -1.648 6.544 c
-1.648 6.058 -1.254 5.661 -0.765 5.661 c
f
Q
q 1 0 0 1 327.288 128.159 cm
0 0 m
0 -10.296 l
S
Q
1.5 w
q 1 0 0 1 36 735.9 cm
0 0 m
540 0 l
S
Q
q 1 0 0 1 514.0979 771.3588 cm
0 0 m
1.668 0 l
1.668 1.862 l
3.88 3.007 l
3.88 0 l
5.878 0 l
5.878 -1.649 l
3.88 -1.649 l
3.88 -7.002 l
3.88 -7.235 3.889 -7.436 3.909 -7.604 c
3.928 -7.772 3.973 -7.914 4.045 -8.031 c
4.116 -8.147 4.222 -8.234 4.365 -8.292 c
4.507 -8.351 4.701 -8.38 4.946 -8.38 c
5.102 -8.38 5.257 -8.377 5.412 -8.37 c
5.568 -8.364 5.722 -8.341 5.878 -8.302 c
5.878 -10.009 l
5.632 -10.035 5.393 -10.061 5.16 -10.087 c
4.927 -10.113 4.688 -10.125 4.442 -10.125 c
3.86 -10.125 3.391 -10.07 3.036 -9.961 c
2.68 -9.851 2.402 -9.689 2.202 -9.476 c
2.001 -9.263 1.865 -8.994 1.794 -8.671 c
1.723 -8.348 1.681 -7.979 1.668 -7.565 c
1.668 -1.649 l
0 -1.649 l
h
f
Q
q 1 0 0 1 520.5963 775.1804 cm
0 0 m
2.211 0.98 l
2.211 -5.141 l
2.25 -5.141 l
2.522 -4.688 2.926 -4.31 3.462 -4.006 c
3.999 -3.702 4.597 -3.55 5.257 -3.55 c
6.356 -3.55 7.222 -3.834 7.856 -4.403 c
8.49 -4.973 8.807 -5.826 8.807 -6.964 c
8.807 -13.85 l
6.595 -13.85 l
6.595 -7.546 l
6.569 -6.757 6.401 -6.185 6.091 -5.829 c
5.781 -5.473 5.296 -5.296 4.636 -5.296 c
4.261 -5.296 3.925 -5.363 3.627 -5.499 c
3.33 -5.635 3.078 -5.823 2.871 -6.062 c
2.664 -6.301 2.502 -6.583 2.386 -6.906 c
2.27 -7.229 2.211 -7.572 2.211 -7.934 c
2.211 -13.85 l
0 -13.85 l
h
f
Q
q 1 0 0 1 532.4869 765.7722 cm
0 0 m
0 -0.388 0.055 -0.763 0.165 -1.125 c
0.275 -1.487 0.44 -1.804 0.659 -2.075 c
0.879 -2.347 1.157 -2.563 1.494 -2.725 c
1.83 -2.887 2.231 -2.968 2.696 -2.968 c
3.343 -2.968 3.863 -2.829 4.258 -2.551 c
4.652 -2.273 4.946 -1.856 5.14 -1.3 c
7.236 -1.3 l
7.119 -1.842 6.919 -2.328 6.634 -2.754 c
6.35 -3.181 6.007 -3.54 5.606 -3.831 c
5.205 -4.122 4.756 -4.342 4.258 -4.491 c
3.76 -4.639 3.24 -4.714 2.696 -4.714 c
1.908 -4.714 1.209 -4.584 0.602 -4.326 c
-0.007 -4.067 -0.521 -3.705 -0.941 -3.24 c
-1.361 -2.774 -1.678 -2.218 -1.891 -1.571 c
-2.105 -0.924 -2.211 -0.213 -2.211 0.563 c
-2.211 1.273 -2.098 1.95 -1.872 2.59 c
-1.646 3.23 -1.323 3.792 -0.902 4.278 c
-0.482 4.762 0.026 5.147 0.621 5.432 c
1.216 5.716 1.888 5.858 2.638 5.858 c
3.427 5.858 4.135 5.693 4.762 5.364 c
5.389 5.034 5.91 4.598 6.324 4.054 c
6.738 3.511 7.038 2.887 7.226 2.182 c
7.413 1.477 7.462 0.75 7.371 0 c
h
5.16 1.455 m
5.134 1.804 5.06 2.14 4.937 2.464 c
4.814 2.787 4.646 3.068 4.432 3.308 c
4.219 3.547 3.961 3.741 3.656 3.89 c
3.352 4.038 3.013 4.112 2.638 4.112 c
2.25 4.112 1.898 4.045 1.581 3.909 c
1.264 3.773 0.993 3.586 0.766 3.346 c
0.54 3.107 0.359 2.825 0.223 2.502 c
0.087 2.179 0.013 1.83 0 1.455 c
h
f
Q
q 1 0 0 1 540.576 771.3588 cm
0 0 m
2.076 0 l
2.076 -1.94 l
2.114 -1.94 l
2.179 -1.668 2.305 -1.403 2.493 -1.144 c
2.68 -0.886 2.906 -0.65 3.172 -0.436 c
3.437 -0.223 3.731 -0.052 4.054 0.078 c
4.377 0.207 4.707 0.272 5.044 0.272 c
5.302 0.272 5.48 0.265 5.577 0.252 c
5.674 0.239 5.774 0.226 5.877 0.214 c
5.877 -1.92 l
5.722 -1.895 5.564 -1.872 5.403 -1.852 c
5.24 -1.833 5.082 -1.823 4.927 -1.823 c
4.552 -1.823 4.2 -1.898 3.87 -2.046 c
3.54 -2.195 3.252 -2.415 3.007 -2.706 c
2.761 -2.997 2.567 -3.356 2.425 -3.782 c
2.282 -4.209 2.211 -4.701 2.211 -5.257 c
2.211 -10.029 l
0 -10.029 l
h
f
Q
q 1 0 0 1 547.2996 771.3588 cm
0 0 m
2.095 0 l
2.095 -1.396 l
2.153 -1.396 l
2.321 -1.151 2.502 -0.924 2.696 -0.718 c
2.89 -0.511 3.107 -0.337 3.346 -0.194 c
3.585 -0.052 3.86 0.062 4.171 0.146 c
4.481 0.23 4.836 0.272 5.238 0.272 c
5.845 0.272 6.411 0.136 6.935 -0.135 c
7.459 -0.407 7.83 -0.828 8.05 -1.396 c
8.425 -0.879 8.858 -0.472 9.35 -0.174 c
9.841 0.123 10.456 0.272 11.193 0.272 c
12.253 0.272 13.077 0.013 13.666 -0.504 c
14.254 -1.021 14.548 -1.888 14.548 -3.103 c
14.548 -10.029 l
12.337 -10.029 l
12.337 -4.17 l
12.337 -3.77 12.324 -3.404 12.298 -3.074 c
12.272 -2.745 12.198 -2.46 12.076 -2.221 c
11.952 -1.982 11.768 -1.797 11.523 -1.668 c
11.276 -1.539 10.941 -1.474 10.514 -1.474 c
9.763 -1.474 9.22 -1.707 8.884 -2.172 c
8.548 -2.638 8.38 -3.297 8.38 -4.151 c
8.38 -10.029 l
6.169 -10.029 l
6.169 -3.589 l
6.169 -2.89 6.042 -2.363 5.79 -2.008 c
5.538 -1.652 5.076 -1.474 4.403 -1.474 c
4.119 -1.474 3.844 -1.532 3.579 -1.649 c
3.314 -1.765 3.081 -1.933 2.881 -2.153 c
2.68 -2.373 2.518 -2.645 2.395 -2.968 c
2.273 -3.291 2.211 -3.66 2.211 -4.073 c
2.211 -10.029 l
0 -10.029 l
h
f
Q
q 1 0 0 1 567.8034 761.0585 cm
0 0 m
-0.802 0 -1.517 0.133 -2.144 0.398 c
-2.771 0.663 -3.301 1.028 -3.734 1.494 c
-4.168 1.959 -4.497 2.515 -4.724 3.162 c
-4.95 3.808 -5.063 4.52 -5.063 5.296 c
-5.063 6.058 -4.95 6.763 -4.724 7.41 c
-4.497 8.057 -4.168 8.613 -3.734 9.078 c
-3.301 9.544 -2.771 9.909 -2.144 10.175 c
-1.517 10.439 -0.802 10.572 0 10.572 c
0.801 10.572 1.516 10.439 2.144 10.175 c
2.771 9.909 3.301 9.544 3.734 9.078 c
4.167 8.613 4.497 8.057 4.724 7.41 c
4.949 6.763 5.062 6.058 5.062 5.296 c
5.062 4.52 4.949 3.808 4.724 3.162 c
4.497 2.515 4.167 1.959 3.734 1.494 c
3.301 1.028 2.771 0.663 2.144 0.398 c
1.516 0.133 0.801 0 0 0 c
0 1.746 m
0.492 1.746 0.918 1.85 1.28 2.056 c
1.642 2.263 1.939 2.534 2.172 2.871 c
2.405 3.207 2.576 3.586 2.686 4.006 c
2.796 4.426 2.852 4.856 2.852 5.296 c
2.852 5.722 2.796 6.149 2.686 6.576 c
2.576 7.003 2.405 7.381 2.172 7.711 c
1.939 8.04 1.642 8.308 1.28 8.516 c
0.918 8.723 0.492 8.826 0 8.826 c
-0.492 8.826 -0.918 8.723 -1.28 8.516 c
-1.643 8.308 -1.94 8.04 -2.173 7.711 c
-2.405 7.381 -2.577 7.003 -2.687 6.576 c
-2.797 6.149 -2.852 5.722 -2.852 5.296 c
-2.852 4.856 -2.797 4.426 -2.687 4.006 c
-2.577 3.586 -2.405 3.207 -2.173 2.871 c
-1.94 2.534 -1.643 2.263 -1.28 2.056 c
-0.918 1.85 -0.492 1.746 0 1.746 c
f
Q
q 1 0 0 1 520.393 753.637 cm
0 0 m
-0.142 0.276 -0.332 0.505 -0.57 0.685 c
-0.808 0.866 -1.081 0.998 -1.39 1.081 c
-1.699 1.165 -2.028 1.207 -2.375 1.207 c
-2.646 1.207 -2.919 1.178 -3.196 1.12 c
-3.473 1.062 -3.727 0.965 -3.959 0.83 c
-4.19 0.695 -4.377 0.518 -4.518 0.299 c
-4.66 0.08 -4.731 -0.19 -4.731 -0.511 c
-4.731 -0.782 -4.663 -1.011 -4.528 -1.197 c
-4.393 -1.384 -4.223 -1.541 -4.017 -1.67 c
-3.811 -1.799 -3.586 -1.905 -3.341 -1.989 c
-3.096 -2.073 -2.871 -2.14 -2.665 -2.192 c
-1.043 -2.558 l
-0.695 -2.61 -0.351 -2.703 -0.01 -2.839 c
0.331 -2.974 0.634 -3.151 0.898 -3.369 c
1.162 -3.589 1.377 -3.859 1.545 -4.181 c
1.712 -4.502 1.796 -4.883 1.796 -5.32 c
1.796 -5.86 1.674 -6.321 1.429 -6.701 c
1.184 -7.08 0.872 -7.389 0.492 -7.628 c
0.112 -7.866 -0.316 -8.036 -0.792 -8.139 c
-1.268 -8.242 -1.738 -8.294 -2.201 -8.294 c
-3.373 -8.294 -4.323 -8.017 -5.05 -7.464 c
-5.777 -6.91 -6.192 -6.021 -6.295 -4.799 c
-5.078 -4.799 l
-5.027 -5.622 -4.728 -6.244 -4.181 -6.662 c
-3.634 -7.08 -2.955 -7.29 -2.143 -7.29 c
-1.847 -7.29 -1.542 -7.257 -1.226 -7.193 c
-0.911 -7.129 -0.618 -7.019 -0.347 -6.865 c
-0.077 -6.71 0.145 -6.514 0.319 -6.276 c
0.492 -6.037 0.579 -5.745 0.579 -5.397 c
0.579 -5.101 0.518 -4.853 0.396 -4.653 c
0.273 -4.454 0.109 -4.286 -0.096 -4.152 c
-0.303 -4.017 -0.538 -3.904 -0.801 -3.814 c
-1.065 -3.724 -1.332 -3.646 -1.603 -3.582 c
-3.167 -3.234 l
-3.566 -3.131 -3.933 -3.013 -4.267 -2.877 c
-4.603 -2.742 -4.895 -2.575 -5.146 -2.375 c
-5.397 -2.176 -5.593 -1.931 -5.735 -1.641 c
-5.877 -1.351 -5.947 -0.994 -5.947 -0.57 c
-5.947 -0.068 -5.835 0.364 -5.609 0.724 c
-5.384 1.084 -5.092 1.374 -4.731 1.593 c
-4.371 1.812 -3.968 1.973 -3.524 2.076 c
-3.08 2.179 -2.639 2.23 -2.201 2.23 c
-1.699 2.23 -1.233 2.166 -0.801 2.037 c
-0.37 1.909 0.01 1.709 0.338 1.439 c
0.666 1.168 0.927 0.833 1.12 0.434 c
1.313 0.035 1.422 -0.434 1.448 -0.975 c
0.232 -0.975 l
0.219 -0.602 0.141 -0.277 0 0 c
f
Q
q 1 0 0 1 529.0824 754.2067 cm
0 0 m
-0.451 0.424 -1.081 0.637 -1.892 0.637 c
-2.472 0.637 -2.98 0.515 -3.418 0.27 c
-3.856 0.025 -4.219 -0.296 -4.509 -0.695 c
-4.799 -1.094 -5.018 -1.548 -5.165 -2.057 c
-5.314 -2.565 -5.387 -3.083 -5.387 -3.611 c
-5.387 -4.139 -5.314 -4.657 -5.165 -5.165 c
-5.018 -5.674 -4.799 -6.128 -4.509 -6.527 c
-4.219 -6.926 -3.856 -7.248 -3.418 -7.492 c
-2.98 -7.737 -2.472 -7.859 -1.892 -7.859 c
-1.519 -7.859 -1.165 -7.789 -0.83 -7.647 c
-0.496 -7.505 -0.2 -7.309 0.058 -7.058 c
0.315 -6.807 0.528 -6.508 0.695 -6.16 c
0.862 -5.812 0.965 -5.433 1.004 -5.021 c
2.221 -5.021 l
2.053 -6.231 1.609 -7.174 0.888 -7.85 c
0.167 -8.526 -0.76 -8.864 -1.892 -8.864 c
-2.652 -8.864 -3.325 -8.725 -3.91 -8.448 c
-4.496 -8.172 -4.989 -7.795 -5.387 -7.319 c
-5.787 -6.842 -6.089 -6.285 -6.295 -5.648 c
-6.501 -5.011 -6.604 -4.332 -6.604 -3.611 c
-6.604 -2.89 -6.501 -2.211 -6.295 -1.574 c
-6.089 -0.936 -5.787 -0.38 -5.387 0.096 c
-4.989 0.573 -4.496 0.952 -3.91 1.236 c
-3.325 1.519 -2.652 1.661 -1.892 1.661 c
-0.824 1.661 0.08 1.377 0.82 0.811 c
1.561 0.244 2.002 -0.611 2.143 -1.757 c
0.927 -1.757 l
0.759 -1.011 0.45 -0.425 0 0 c
f
Q
533.273 745.614 -1.216 9.964 re
f
q 1 0 0 1 535.5416 748.9061 cm
0 0 m
0.122 -0.47 0.319 -0.891 0.589 -1.265 c
0.859 -1.638 1.2 -1.947 1.612 -2.192 c
2.024 -2.436 2.52 -2.559 3.099 -2.559 c
3.988 -2.559 4.683 -2.327 5.185 -1.863 c
5.687 -1.4 6.034 -0.782 6.227 -0.009 c
7.444 -0.009 l
7.187 -1.142 6.714 -2.018 6.025 -2.636 c
5.336 -3.254 4.361 -3.563 3.099 -3.563 c
2.314 -3.563 1.635 -3.424 1.062 -3.148 c
0.489 -2.871 0.022 -2.491 -0.338 -2.008 c
-0.698 -1.525 -0.965 -0.965 -1.139 -0.328 c
-1.313 0.309 -1.4 0.981 -1.4 1.69 c
-1.4 2.346 -1.313 2.99 -1.139 3.621 c
-0.965 4.251 -0.698 4.814 -0.338 5.31 c
0.022 5.806 0.489 6.205 1.062 6.508 c
1.635 6.81 2.314 6.961 3.099 6.961 c
3.897 6.961 4.579 6.8 5.146 6.478 c
5.713 6.156 6.173 5.735 6.527 5.214 c
6.881 4.692 7.135 4.094 7.29 3.418 c
7.444 2.742 7.508 2.056 7.483 1.362 c
-0.183 1.362 l
-0.183 0.924 -0.123 0.47 0 0 c
6.025 3.717 m
5.877 4.142 5.667 4.519 5.397 4.847 c
5.127 5.175 4.799 5.439 4.412 5.639 c
4.026 5.838 3.588 5.938 3.099 5.938 c
2.597 5.938 2.153 5.838 1.767 5.639 c
1.381 5.439 1.052 5.175 0.782 4.847 c
0.512 4.519 0.296 4.139 0.135 3.708 c
-0.026 3.276 -0.132 2.836 -0.183 2.385 c
6.266 2.385 l
6.253 2.848 6.173 3.293 6.025 3.717 c
f
Q
q 1 0 0 1 544.8972 755.5778 cm
0 0 m
0 -1.718 l
0.038 -1.718 l
0.27 -1.114 0.682 -0.628 1.274 -0.261 c
1.867 0.106 2.517 0.289 3.225 0.289 c
3.92 0.289 4.502 0.199 4.972 0.019 c
5.442 -0.161 5.819 -0.415 6.102 -0.744 c
6.385 -1.072 6.585 -1.474 6.701 -1.95 c
6.816 -2.427 6.874 -2.961 6.874 -3.553 c
6.874 -9.964 l
5.658 -9.964 l
5.658 -3.746 l
5.658 -3.321 5.619 -2.926 5.542 -2.559 c
5.465 -2.192 5.329 -1.873 5.136 -1.603 c
4.943 -1.332 4.683 -1.12 4.354 -0.965 c
4.026 -0.811 3.617 -0.734 3.128 -0.734 c
2.639 -0.734 2.205 -0.821 1.825 -0.995 c
1.445 -1.168 1.123 -1.407 0.859 -1.709 c
0.595 -2.012 0.389 -2.372 0.241 -2.79 c
0.093 -3.209 0.013 -3.663 0 -4.152 c
0 -9.964 l
-1.216 -9.964 l
-1.216 0 l
h
f
Q
q 1 0 0 1 557.0623 755.5778 cm
0 0 m
0 -1.024 l
-2.028 -1.024 l
-2.028 -7.744 l
-2.028 -8.143 -1.973 -8.455 -1.863 -8.68 c
-1.754 -8.906 -1.48 -9.031 -1.043 -9.057 c
-0.695 -9.057 -0.347 -9.038 0 -8.999 c
0 -10.022 l
-0.18 -10.022 -0.36 -10.028 -0.54 -10.041 c
-0.721 -10.054 -0.901 -10.06 -1.081 -10.06 c
-1.892 -10.06 -2.459 -9.903 -2.781 -9.588 c
-3.103 -9.273 -3.257 -8.69 -3.244 -7.84 c
-3.244 -1.024 l
-4.982 -1.024 l
-4.982 0 l
-3.244 0 l
-3.244 1.873 l
-2.028 2.993 l
-2.028 0 l
h
f
Q
559.09 745.614 -1.216 9.964 re
f
q 1 0 0 1 562.6208 754.5542 cm
0 0 m
0 -8.941 l
-1.216 -8.941 l
-1.216 0 l
-2.916 0 l
-2.916 1.024 l
-1.216 1.024 l
-1.216 1.931 l
-1.216 2.356 -1.185 2.749 -1.12 3.109 c
-1.056 3.469 -0.934 3.778 -0.753 4.036 c
-0.573 4.293 -0.325 4.493 -0.01 4.635 c
0.306 4.776 0.708 4.847 1.197 4.847 c
1.378 4.847 1.545 4.84 1.7 4.827 c
1.854 4.814 2.028 4.795 2.221 4.77 c
2.221 3.727 l
2.054 3.753 1.899 3.775 1.758 3.795 c
1.616 3.814 1.474 3.823 1.332 3.823 c
0.997 3.823 0.74 3.772 0.56 3.669 c
0.38 3.566 0.248 3.428 0.164 3.254 c
0.081 3.08 0.032 2.877 0.019 2.646 c
0.006 2.414 0 2.163 0 1.892 c
0 1.024 l
1.969 1.024 l
1.969 0 l
h
f
Q
566.306 745.614 -1.216 9.964 re
f
q 1 0 0 1 573.7792 754.2067 cm
0 0 m
-0.45 0.424 -1.081 0.637 -1.892 0.637 c
-2.471 0.637 -2.98 0.515 -3.417 0.27 c
-3.855 0.025 -4.219 -0.296 -4.509 -0.695 c
-4.798 -1.094 -5.018 -1.548 -5.165 -2.057 c
-5.314 -2.565 -5.387 -3.083 -5.387 -3.611 c
-5.387 -4.139 -5.314 -4.657 -5.165 -5.165 c
-5.018 -5.674 -4.798 -6.128 -4.509 -6.527 c
-4.219 -6.926 -3.855 -7.248 -3.417 -7.492 c
-2.98 -7.737 -2.471 -7.859 -1.892 -7.859 c
-1.519 -7.859 -1.165 -7.789 -0.83 -7.647 c
-0.496 -7.505 -0.2 -7.309 0.058 -7.058 c
0.316 -6.807 0.527 -6.508 0.695 -6.16 c
0.863 -5.812 0.966 -5.433 1.004 -5.021 c
2.221 -5.021 l
2.054 -6.231 1.609 -7.174 0.888 -7.85 c
0.168 -8.526 -0.76 -8.864 -1.892 -8.864 c
-2.652 -8.864 -3.325 -8.725 -3.91 -8.448 c
-4.496 -8.172 -4.989 -7.795 -5.387 -7.319 c
-5.787 -6.842 -6.089 -6.285 -6.295 -5.648 c
-6.501 -5.011 -6.604 -4.332 -6.604 -3.611 c
-6.604 -2.89 -6.501 -2.211 -6.295 -1.574 c
-6.089 -0.936 -5.787 -0.38 -5.387 0.096 c
-4.989 0.573 -4.496 0.952 -3.91 1.236 c
-3.325 1.519 -2.652 1.661 -1.892 1.661 c
-0.824 1.661 0.081 1.377 0.821 0.811 c
1.561 0.244 2.002 -0.611 2.144 -1.757 c
0.927 -1.757 l
0.76 -1.011 0.451 -0.425 0 0 c
f
Q
q 1 0 0 1 559.7008 758.9197 cm
0 0 m
-0.608 -1.951 l
-1.825 -1.951 l
-1.216 0 l
h
f
Q
q 1 0 0 1 566.9115 758.9197 cm
0 0 m
-0.608 -1.951 l
-1.824 -1.951 l
-1.216 0 l
h
f
Q
q 1 0 0 1 533.8826 758.9197 cm
0 0 m
-0.608 -1.951 l
-1.825 -1.951 l
-1.216 0 l
h
f
Q
endstream
endobj
9 0 obj
<>
endobj
7 0 obj
[/ICCBased 15 0 R]
endobj
15 0 obj
<>stream
HuTKtKKJI,t(4K%ҹH4J#Ғ(H
wqyy~3̙g<3 Y9El
@ ]!O-@ \+BVKK
:OX~WCaiHKL 0qY `5 ck
X] x=8 X Ŀ>.f#aPn D^{y8 dpH st:Yc xc
IV?S!:_9[YbQP~+rA
ShHht^
'0߅kYXY9Yqqpl'WzEE$%D>,^|t*K)%/`\ҫ:&D[7dplDa5|mb4,yy{e5
3⚅,t+whlA
mk
xYUH&%Ȥ
qO'Mz3KT@v[NUnn^\o]abTrtlmE]e~U+jאZ:zaqi5};CS[\_ۆwCaQ1;>L$Lz}4:%8M7l̎Χ/}XT^]X>\Ym[n!ycskkƶʷ;v{pIs0Xݯ3s&$WWW*)!$$%!e$cHNOAKIMEqƕ;KLw@YX;ؚ8^+DspfKOTCPpJ%D=++O%$*8IZ\Z^UK_wL"dx]} >9=;s_G8/̹N!Gz[<=2|B}PQzlH0Wc(Een|Pds::5&89yFT"od䳔i/ZK^&gd:fgQl
kJХeJ*+篍kj5U[ZUh0|em6]B@`PpH?QM1Msψ*iϛ.Z[JYZ)X-]RѺپw?@?5 ǖ'vNg
W3gLC#u!MMMEvAms˔FVNA̝GLwA̬,llؿsݛnͽ+!B²" 'R&k?3?4+:6oT\ұڿ6VʝoF?LT;:>::>:;eqvx^sawݥʕ'_ EFO\DKLtAnFF)F|ԭ6\`@z?m+F;LwiA hy͖)Mgw~_
@ZH_XA,"F)%/*9aZ:Q,\B^_AU2
*'[jo5[uR1uh`fm$1xJgBdrltlyyEe$feg-g#`dGbwj0TOC9; ܨݿxz6zx8IP=A!.aAxۑ ϊ}bG-ޒēx`G/Ԝq_O?0"۬խЮ˯ǰı²µŶȷӹۺ 0@RfzƏǦȾ*GcЀџҿ'LsٛFsM6+1MZ:{ T?~ò~i~L}~cbA~Dad~ty~W~O>~\/~|~`C x}%H}1X}%z}K}
{N}<_~7A~-ψ||Dz|+E|[s|z}^}wO@}-~ċ {Gu{Dz{]Ĭ{f{Zx|[]|ϕM?}R<}Ǝz]YzHħz|z={LNw{\|=>|v|ېI8z/r
z;bz'sMzd6zɬqv{D[{0>|;|yyaIy?yazYvzݮ[{^=c{ФI{R*y߄yfUy`VyyuKzZi{<{z%zȎ~+~ }͇}W0}3}HtЄ}Zk}=~zɇ }!~Єd*s}Y<9wpSwuuVrUW؈|;,뇔{RsѲ;:8q)PCV:4.8Ȅ2?UpVu9ScbփR.ՁNn U388A/ͬδz6߆өn1T\e7݀tXT)$̯̕6;eCʷˆ imw3SƀV7M
\lGNػځNāa5tNzlߴS<H6*